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1.Product Description
| Intermediate 1 code name | NB-8(S,S) | Intermediate 1 English name | (S)-2-chloro-1-((S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol |
| Intermediate 1 CAS | 1315508-96-3 | Intermediate 1 structural formula |  |
| Intermediate 2 code name | NB-8(R,S) | Intermediate 2 English name | (R)-2-chloro-1-((S)-6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol |
| Intermediate 2 CAS | 1315508-95-2 | Intermediate 2 structural formula |  |
| Intermediate 3 code name | NB-8(R,R) | Intermediate 3 English name | (R)-2-chloro-1-((R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol |
| Intermediate 3 CAS | 1315508-94-1 | Intermediate 3 structural formula |   |
| Intermediate 4 code name | NB-8(S,R) | Intermediate 4 English name | (S)-2-chloro-1-((R)-6-fluoro-3,4-dihydro-2H-chromen-2-yl)ethanol |
| Intermediate 4 CAS | 1315508-93-0 | Intermediate 4 structural formula |  |
| level | Chemical grade | appearance | White solid |
| Package | 25 kg/barrel | Shelf life | 2 years |
| The purity | ≥99% | Store condition | Store in a cool, dry and well-ventilated place |
The Nebivolol intermediate has two chiral intermediates, it has four enantiomers. Nebivolol is a selective β1 adrenergic receptor antagonist with vasodilatatory activity and no endogenous sensory activity. It is used in the treatment of patients with mild to moderate hypertension, as well as in the treatment of angina pectoris and congestive heart failure.
The company uses keto reductase, the use of synzyme catalytic method to produce nebilol intermediates, products with green, environmental protection, high chiral purity.
產(chǎn)品結(jié)構(gòu)式
2.Naturalness test report and COA
3.Product Application:
It can be used as medicine intermediate and so on.
